Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.

When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.

The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.

• Three new Ebola cases confirmed in eastern Congo - Reuters
  Mon, 18 Oct 2021 08:31 GMT
• New Ebola case confirmed in eastern Congo - Reuters
  Sat, 09 Oct 2021 07:00 GMT
• Second Ebola case confirmed in eastern Congo - Reuters
  Thu, 14 Oct 2021 16:56 GMT
• Analysis of 2021 Ebola outbreak reveals long-term dormant infections - News-Medical.Net
  Sun, 19 Sep 2021 07:00 GMT
• UNICEF DRC COVID-19 and Ebola Situation Report No.2, 11-15 October 2021 - Democratic Republic of the Congo - ReliefWeb
  Sat, 16 Oct 2021 14:46 GMT
• Outbreak Brief 1: Ebola virus disease (EVD) in the Democratic Republic of Congo – Africa CDC - africacdc.org
  Fri, 15 Oct 2021 07:00 GMT
• Ebola resurfaced: some viruses are never really gone - Cosmos Magazine
  Mon, 04 Oct 2021 07:00 GMT
• A lesson from Ebola | Opinion | bradfordera.com - Bradford Era
  Thu, 30 Sep 2021 07:00 GMT
• New Fatal Ebola Case In DRC, Raising Fears Of Fresh Outbreak - IFLScience
  Tue, 12 Oct 2021 15:14 GMT
• WHO employees took part in Congo sex abuses in Ebola crisis, report says - CNN
  Tue, 28 Sep 2021 07:00 GMT
• WHO Reports On Sex Scandal Involving Its Staff During Congo's Ebola Crisis : Goats and Soda - NPR
  Wed, 29 Sep 2021 07:00 GMT
• Papers show what lay behind Condé regime's Ebola denialism in Guinea - The Conversation CA
  Mon, 11 Oct 2021 15:07 GMT
• DR Congo starts Ebola vaccinations - Global Times
  Thu, 14 Oct 2021 09:43 GMT
• New studies propose policy changes for Ebola vaccination in Africa - Devex
  Thu, 23 Sep 2021 07:00 GMT
• Op-Ed: A lesson from Ebola in 2015 will be key to ending COVID-19 - Los Angeles Times
  Sat, 25 Sep 2021 07:00 GMT

• PRO/AH/EDR> Ebola update (44): Burkina Faso ex Cote d'Ivoire, 2nd case, NOT
  Mon, 30 Aug 2021 11:01:25 -0400
  Ebola -- Burkina Faso
  On 22 Aug 2021, the Ministry of Health informed the population of the admission to the Medical Emergencies of the Bogodogo University Hospital (CHU-B) of a 22-year-old patient who had stayed in the Republic of [Cote d'Ivoire]. The diagnostic procedure consisted of sampling analysis at the National Reference Laboratory for Viral Haemorrhagic Fever (LNR-FHV at the Muraz Centre) and the Pasteur Institute of Dakar for confirmation. The results obtained make it possible to permanently rule out

• Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2 Fri, 15 Oct 2021 06:00:00 -0400
  The C-type lectin receptor DC-SIGN is a pattern recognition receptor expressed on macrophages and dendritic cells. It has been identified as a promiscuous entry receptor for many pathogens, including epidemic and pandemic viruses such as SARS-CoV-2, Ebola virus, and HIV-1. In the context of the recent SARS-CoV-2 pandemic, DC-SIGN-mediated virus dissemination and stimulation of innate immune responses has been implicated as a potential factor in the development of severe COVID-19. Inhibition of...
• Bioterrorism Fri, 15 Oct 2021 06:00:00 -0400
  Bioterrorism is the deliberate release of viruses, bacteria, toxins, or fungi with the goal of causing panic, mass casualties, or severe economic disruption. From 1981 to 2018, there were 37 bioterrorist attacks worldwide. The Centers for Disease Control and Prevention (CDC) lists anthrax, botulism, plague, smallpox, tularemia, and viral hemorrhagic fevers as category A agents that are the greatest risk to national security. An emerging infectious disease (e.g., novel respiratory virus) may also...
• Infectious disease in an era of global change Thu, 14 Oct 2021 06:00:00 -0400
  The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods around the globe. The 2003 severe acute respiratory syndrome coronavirus outbreak, the 2009 swine flu pandemic, the 2012 Middle East respiratory syndrome coronavirus outbreak, the 2013-2016 Ebola virus disease epidemic in West Africa and the 2015 Zika virus disease epidemic all resulted in substantial morbidity and...
• Accessing unproven interventions in the COVID-19 pandemic: discussion on the ethics of 'compassionate therapies' in times of catastrophic pandemics Thu, 14 Oct 2021 06:00:00 -0400
  Since the onset of the SARS-CoV-2 pandemic, an array of off-label interventions has been used to treat patients, either provided as compassionate care or tested in clinical trials. There is a challenge in determining the justification for conducting randomised controlled trials over providing compassionate use in an emergency setting. A rapid and more accurate evaluation tool is needed to assess the effect of these treatments. Given the similarity to the Ebola Virus Disease (EVD) pandemic in...
• Increased human-animal interface & emerging zoonotic diseases: An enigma requiring multi-sectoral efforts to address Wed, 13 Oct 2021 06:00:00 -0400
  Increased human-animal interfaces impose threats on human life by creating scope for the emergence and resurgence of many infectious diseases. Over the last two decades, emergence of novel viral diseases such as SARS, influenza A/H1N1(09) pdm; MERS; Nipah virus disease; Ebola haemorrhagic fever and the current COVID-19 has resulted in massive outbreaks, epidemics and pandemics thereby causing profound losses of human life, health and economy. The current COVID-19 pandemic has affected more than...
• Establishment of Intestinal Organoid from Rousettus leschenaultii and the Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus Wed, 13 Oct 2021 06:00:00 -0400
  Various pathogens, such as Ebola virus, Marburg virus, Nipah virus, Hendra virus, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and SARS-CoV-2, are threatening human health worldwide. The natural hosts of these pathogens are thought to be bats. The rousette bat, a megabat, is thought to be a natural reservoir of filoviruses, including Ebola and Marburg viruses. Additionally, the rousette bat showed a transient infection in the...
• The impact of the COVID-19 pandemic on hospital utilisation in Sierra Leone Tue, 12 Oct 2021 06:00:00 -0400
  CONCLUSION: The study demonstrated a decrease in hospital utilisation during COVID-19, the decrease is less than reported in other countries during COVID-19 and less than reported during the Ebola epidemic.
• The genetic impact of an Ebola outbreak on a wild gorilla population Tue, 12 Oct 2021 06:00:00 -0400
  CONCLUSION: This study offers the first insight to the genetics of a wild great ape population before and after an Ebola outbreak using target capture experiments from fecal samples, and presents a list of candidate loci that may have facilitated their survival.
• Identification and Characterization of a Novel Single Domain Antibody Against Ebola Virus Mon, 11 Oct 2021 06:00:00 -0400
  Ebola virus (EBOV) belongs to the Filoviridae family and causes severe illnesses such as hemorrhagic fever with a high mortality rate up to 90%. Now two antibody drugs termed Inmazeb and Ebanga have been approved for treating EBOV infection. However, clinical studies have demonstrated that the mortality rate of the patients who received these two antibody drugs remains above 30%. Therefore, novel therapeutics with better efficacy is still desired. The isolated human IgG1 constant domain 2 (CH2...
• Expanded Histopathology and Tropism of Ebola Virus in the Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production and Early Viral Replication in liver Sat, 09 Oct 2021 06:00:00 -0400
  The pathogenesis of Ebola virus disease (EVD) is still incomplete, although the non-human primate model has been studied for more than 4 decades. To further investigate EVD pathogenesis, a natural history study has been conducted using 27 Chinese-origin rhesus macaques. Of them, 24 macaques were exposed intramuscularly to Kikwit Ebola virus (EBOV) and euthanized at pre-determined timepoints or when end stage clinical disease criteria were met, while 3 other sham-exposed macaques were euthanized...