Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.
When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.
The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.
- Véronique Tadjo's 'In The Company Of Men' Focuses On West Africa's Ebola Outbreak - NPR
Wed, 24 Feb 2021 21:57 GMT
- WHO | Ebola virus disease – Guinea - WHO/Europe
Wed, 17 Feb 2021 23:44 GMT
- Why Ebola is back in Guinea and why the response must be different this time - The Conversation CA
Sun, 21 Feb 2021 08:34 GMT
- Ebola virus disease – Democratic Republic of the Congo - WHO/Europe
Wed, 10 Feb 2021 08:00 GMT
- Guinea Declares Ebola Outbreak - NPR
Sun, 14 Feb 2021 08:00 GMT
- Multiple Countries | Ebola Virus Disease (EVD) Outbreak: Preparedness and Response - Emergency Appeal: n° MDREBOLA21 (19 February 2021) - Guinea - ReliefWeb
Sat, 20 Feb 2021 18:44 GMT
- Disease outbreak news: Ebola virus disease – Guinea (17 February 2021) - Guinea - ReliefWeb
Thu, 18 Feb 2021 03:50 GMT
- UNICEF DRC Ebola Situation Report No. 3: 15 - 19 February 2021 - Democratic Republic of the Congo - ReliefWeb
Fri, 19 Feb 2021 08:00 GMT
- New Ebola Outbreak Threatens in Congo - The New York Times
Mon, 22 Feb 2021 08:00 GMT
- Women's groups lead fight against misinformation as Ebola returns to DRC - Democratic Republic of the Congo - ReliefWeb
Wed, 24 Feb 2021 11:52 GMT
- Republic of Guinea - Ebola Virus Disease outbreak (Emergency Response Coordination Centre (ERCC) – DG ECHO Daily Map | 24/02/2021 - Guinea - ReliefWeb
Wed, 24 Feb 2021 16:48 GMT
- What an Ebola outbreak reveals about vaccine inequity - Aljazeera.com
Mon, 22 Feb 2021 14:36 GMT
- Ebola: 20,000 vaccine doses to tackle Guinea outbreak - SciDev.Net
Thu, 25 Feb 2021 14:56 GMT
- Antibodies periodically wax and wane in survivors of Ebola News & Views - Nature.com
Wed, 27 Jan 2021 08:00 GMT
- Ebola is a master of disguise: A druggable pathway the virus uses to trick its way into our organs - Science Daily
Thu, 11 Feb 2021 08:00 GMT
- PRO/AH/EDR> Ebola update (18): Guinea, Congo DR (NK), West Africa
Wed, 24 Feb 2021 14:56:57 -0500
Ebola -- Guinea
Muyembe has been studying the Ebola virus ever since he first laid hands on it in 1976. While investigating a mysterious outbreak near the Ebola River in northern DRC, then known as Zaire, he collected blood samples from ailing villagers.
"Back then, we used our bare hands," with no gloves to hold a syringe, he said in an interview for the Bulletin of the World Health Organization in 2018. In retrospect, he called his survival "extraordinary. If I had not washed my hands, I would have
- What community-based public health approaches in West Africa for COVID-19 epidemic? A reflection based on the African socio-cultural context Wed, 24 Feb 2021 06:00:00 -0500
The social and cultural dimensions of health influence the course of disease and condition the success of health interventions. In Africa, previous epidemics such as Ebola have shown the importance of contextualizing health interventions. This literature review contributes to the reflection on the analysis of community-based interventions in the context of the particularities of West Africa in the fight against the pandemic in COVID-19.
- COVID-19 pandemic, Uganda's story Wed, 24 Feb 2021 06:00:00 -0500
As the COVID-19 pandemic continues to ravage health care systems, economies, livelihoods, and cultures across the world, responses across countries have varied greatly. Uganda adopted its own model taking into consideration its culture, values, environment, socio-economic activities, beliefs, previous successful epidemic experience, and appears a hybrid policy to the Norwegian model. This model of response is perhaps based on Uganda's long experience in successful control of many previous...
- Biological activity-based modeling identifies antiviral leads against SARS-CoV-2 Wed, 24 Feb 2021 06:00:00 -0500
Computational approaches for drug discovery, such as quantitative structure-activity relationship, rely on structural similarities of small molecules to infer biological activity but are often limited to identifying new drug candidates in the chemical spaces close to known ligands. Here we report a biological activity-based modeling (BABM) approach, in which compound activity profiles established across multiple assays are used as signatures to predict compound activity in other assays or...
- Identifying Potentially Beneficial Genetic Mutations Associated with Monophyletic Selective Sweep and a Proof-of-Concept Study with Viral Genetic Data Wed, 24 Feb 2021 06:00:00 -0500
Genetic mutations play a central role in evolution. For a significantly beneficial mutation, a one-time mutation event suffices for the species to prosper and predominate through the process called "monophyletic selective sweep." However, existing methods that rely on counting the number of mutation events to detect selection are unable to find such a mutation in selective sweep. We here introduce a method to detect mutations at the single amino acid/nucleotide level that could be responsible...
- Understanding the long-term evolution and predictors of sequelae of Ebola virus disease survivors in Guinea: A 48-month prospective, longitudinal cohort study (PostEboGui) Tue, 23 Feb 2021 06:00:00 -0500
CONCLUSION: Our findings provide new insight into the long-term clinical complications of EVD and their significant association with symptoms in the acute phase, thus reinforcing the importance of regular, long-term follow-up for EVD survivors.
- Epidemiology of Viral Induced Anterior Uveitis Mon, 22 Feb 2021 06:00:00 -0500
Purpose: Viral agents are the most common cause of infectious anterior uveitis worldwide. The purpose of this review is to analyze the frequency, gender and racial differences of viral anterior uveitis (VAU) in various populations. Methods: Systematized literature review of epidemiological reports of VAU cited in PubMed, EMBASE and the Cochrane Library database published until June 30th, 2020. Results: A total of 12 clinical studies on epidemiology of definite VAU and 36 clinical studies of...
- Modeling and tracking Covid-19 cases using Big Data analytics on HPCC system platformm Mon, 22 Feb 2021 06:00:00 -0500
This project is funded by the US National Science Foundation (NSF) through their NSF RAPID program under the title "Modeling Corona Spread Using Big Data Analytics." The project is a joint effort between the Department of Computer & Electrical Engineering and Computer Science at FAU and a research group from LexisNexis Risk Solutions. The novel coronavirus Covid-19 originated in China in early December 2019 and has rapidly spread to many countries around the globe, with the number of confirmed...
- Ebola virus outbreak preparedness plan for developing Nations: Lessons learnt from affected countries Sun, 21 Feb 2021 06:00:00 -0500
CONCLUSION: Developing countries are particularly vulnerable to major outbreaks of EBOV due to increased international travel and unchecked transmission. The recommended preparedness plan will help developing counties to contain EBOV outbreaks in future.
- Next-generation diagnostics: virus capture facilitates a sensitive viral diagnosis for epizootic and zoonotic pathogens including SARS-CoV-2 Sun, 21 Feb 2021 06:00:00 -0500
CONCLUSIONS: The VirBaits approach showed a high diagnostic performance, also for distantly related viruses. The bait set is modular and expandable according to the favored diagnostics, health sector, or research question. The risk of cross-contamination needs to be taken into consideration. The application of the RNA-baits principle turned out to be user friendly, and even non-experts can easily use the VirBaits workflow. The rapid extension of the established VirBaits set adapted to actual...
- Synthetic and medicinal perspective of quinolines as antiviral agents Sat, 20 Feb 2021 06:00:00 -0500
In current scenario, various heterocycles have come up exhibiting crucial role in various medicinal agents which are valuable for mankind. Out of diverse range of heterocycle, quinoline scaffold have been proved to play an important role in broad range of biological activities. Several drug molecules bearing a quinoline molecule with useful anticancer, antibacterial activities etc have been marketed such as chloroquine, saquinavir etc. Owing to their broad spectrum biological role, various...