Ebola Virus Net is the web resource for anyone interested in ebola. Ebola (Ebola hemorrhagic fever), is a severe, often fatal disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. Ebola is a rare and deadly disease caused by infection with a virus of the family Filoviridae, genus Ebolavirus. There are five identified Ebolavirus species, four of which have caused disease in humans. Ebola is found in several African countries. The first Ebola species was discovered in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, outbreaks have appeared sporadically in Africa. The largest outbreak to date was the epidemic in West Africa, which occurred from December 2013, to January 2016, with 28,646 cases and 11,323 deaths. Other outbreaks in Africa began in the Democratic Republic of the Congo in May 2017 and 2018. In July 2019, the World Health Organization declared the Congo Ebola outbreak a world health emergency.

When an infection does occur in humans, the virus can be spread to others through direct contact with the blood or body fluids of a person who is sick with Ebola, or through contact with objects that have been contaminated with the blood or body fluids of an infected person. Until recent, no vaccines were effective. In December 2016, Ebola was found to be 70–100% prevented by rVSV-ZEBOV vaccine, making it the first proven vaccine against the disease. More than 100,000 people have been vaccinated against Ebola as of 2019.

The objectives of Ebola Virus Net are to be the public and professional information resource for ebola and to serve as a network in the exchange of information and news related to ebola.

• Fears slightly eased after suspected Ebola case transferred to ... - Surinenglish.com
  Fri, 02 Jun 2023 10:29 GMT
• Woman admitted to hospital in Spain with Ebola symptoms - The Olive Press
  Thu, 01 Jun 2023 10:41 GMT
• Patient admitted to San Sebastián hospital finally diagnosed with ... - Euro Weekly News
  Fri, 02 Jun 2023 17:47 GMT
• Tanzania declares end of Marburg viral outbreak - Reuters
  Fri, 02 Jun 2023 14:47 GMT
• Ebola Disease Detected in the Democratic Republic of Congo - Vax-Before-Travel
  Sat, 13 May 2023 07:00 GMT
• World Health Assembly recognizes WHO's work on PRSEAH, calls ... - who.int
  Fri, 02 Jun 2023 12:57 GMT
• Marburg virus and lessons learned during the West Africa Ebola ... - Outbreak News Today
  Fri, 12 May 2023 07:00 GMT
• Tomato-producing states battle ebola, price skyrockets - Punch Newspapers
  Thu, 11 May 2023 07:00 GMT
• Ebola disease caused by Sudan ebolavirus – Uganda - who.int
  Sat, 14 Jan 2023 08:00 GMT
• Should Americans be worried about the recent Ebola outbreak? - Nebraska Medicine
  Tue, 22 Nov 2022 08:00 GMT
• The New Pandemic Fund: Overview and Key Issues for the U.S. - KFF
  Tue, 30 May 2023 13:53 GMT
• The HIV/AIDS fight's far-reaching benefits for global health - US Embassy in Uganda - USEmbassy.gov
  Thu, 01 Jun 2023 07:05 GMT
• 'Ebola is real': Uganda to trial vaccines and shut schools early to contain outbreak - CNN
  Fri, 18 Nov 2022 08:00 GMT
• How the World's Deadliest Ebola Outbreak Unfolded (full ... - YouTube
  Wed, 01 Mar 2023 00:00 GMT
• How the WHO is using radical transparency to change its culture of ‘rampant’ sexual misconduct - Fortune
  Thu, 01 Jun 2023 16:23 GMT

• PRO/AH/EDR> Ebola update (44): Burkina Faso ex Cote d'Ivoire, 2nd case, NOT
  Mon, 30 Aug 2021 11:01:25 -0400
  Ebola -- Burkina Faso
  On 22 Aug 2021, the Ministry of Health informed the population of the admission to the Medical Emergencies of the Bogodogo University Hospital (CHU-B) of a 22-year-old patient who had stayed in the Republic of [Cote d'Ivoire]. The diagnostic procedure consisted of sampling analysis at the National Reference Laboratory for Viral Haemorrhagic Fever (LNR-FHV at the Muraz Centre) and the Pasteur Institute of Dakar for confirmation. The results obtained make it possible to permanently rule out

• A community-based contact isolation strategy to reduce the spread of Ebola virus disease: an analysis of the 2018-2020 outbreak in the Democratic Republic of the Congo Thu, 01 Jun 2023 06:00:00 -0400
  CONCLUSION: The community-based contact isolation strategy used in DRC shows promise as a potentially effective approach for the rapid cessation of EVD transmission, highlighting the importance of rapidly implemented, community-oriented and trust-building control strategies.
• In Vitro and In Vivo Models for Drug Transport Across the Blood-Testis Barrier Wed, 31 May 2023 06:00:00 -0400
  The blood-testis barrier (BTB) is a selectively permeable membrane barrier formed by adjacent Sertoli cells (SCs) in the seminiferous tubules of the testes that develops intercellular junctional complexes to protect developing germ cells from external pressures. However, due to this inherent defense mechanism, the seminiferous tubule lumen can act as a pharmacological sanctuary site for latent viruses (e.g., Ebola, Zika) and cancers (e.g., leukemia). Therefore, it is critical to identify and...
• Reddit and Google Activity Related to Non-COVID Epidemic Diseases Surged at Start of COVID-19 Pandemic: Retrospective Study Wed, 31 May 2023 06:00:00 -0400
  CONCLUSIONS: Google Trends and Reddit can readily be used to evaluate real-time general interest levels in public health related topics, providing a tool to better time and direct public health initiatives that require a receptive target audience. The start of the COVID-19 pandemic correlated with increased public interest in other epidemic infectious diseases. We have demonstrated that for six distinct infectious causes of epidemics over the last two decades, public interest rose substantially...
• Analysis of YouTube^© Videos Regarding Breastfeeding During the Coronavirus Disease (COVID-19) Pandemic Wed, 31 May 2023 06:00:00 -0400
  INTRODUCTION: During the coronavirus disease (COVID-19) pandemic, which has significantly impacted public health, it is crucial to raise awareness and access to accurate information about breastfeeding for healthy growth and development. This descriptive study aimed to evaluate the content, reliability, and quality of YouTube videos on COVID-19 and breastfeeding.
• Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24 Sat, 27 May 2023 06:00:00 -0400
  Members of the Ebolavirus genus demonstrate a marked differences in pathogenicity in humans with Ebola (EBOV) being the most pathogenic, Bundibugyo (BDBV) less pathogenic, and Reston (RESTV) is not known to cause a disease in humans. The VP24 protein encoded by members of the Ebolavirus genus blocks type I interferon (IFN-I) signaling through interaction with host karyopherin alpha nuclear transporters, potentially contributing to virulence. Previously, we demonstrated that BDBV VP24 (bVP24)...
• Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV Sat, 27 May 2023 06:00:00 -0400
  Vesicular stomatitis virus (VSV) remains an attractive platform for a potential HIV-1 vaccine but hurdles remain, such as selection of a highly immunogenic HIV-1 Envelope (Env) with a maximal surface expression on recombinant rVSV particles. An HIV-1 Env chimera with the transmembrane domain (TM) and cytoplasmic tail (CT) of SIVMac239 results in high expression on the approved Ebola vaccine, rVSV-ZEBOV, also harboring the Ebola Virus (EBOV) glycoprotein (GP). Codon-optimized (CO) Env chimeras...
• COVID-19 Vaccine Perceptions among Ebola-Affected Communities in North Kivu, Democratic Republic of the Congo, 2021 Sat, 27 May 2023 06:00:00 -0400
  Populations affected by humanitarian crises and emerging infectious disease outbreaks may have unique concerns and experiences that influence their perceptions toward vaccines. In March 2021, we conducted a survey to examine the perceptions toward COVID-19 vaccines and identify the factors associated with vaccine intention among 631 community members (CMs) and 438 healthcare workers (HCWs) affected by the 2018-2020 Ebola Virus Disease outbreak in North Kivu, Democratic Republic of the Congo. A...
• The Role of Spermidine and Its Key Metabolites in Important, Pathogenic Human Viruses and in Parasitic Infections Caused by Plasmodium falciparum and Trypanosoma brucei Sat, 27 May 2023 06:00:00 -0400
  The triamine spermidine is a key metabolite of the polyamine pathway. It plays a crucial role in many infectious diseases caused by viral or parasitic infections. Spermidine and its metabolizing enzymes, i.e., spermidine/spermine-N¹-acetyltransferase, spermine oxidase, acetyl polyamine oxidase, and deoxyhypusine synthase, fulfill common functions during infection in parasitic protozoa and viruses which are obligate, intracellular parasites. The competition for this important polyamine between...
• Burial workers' perceptions of community resistance and support systems during an Ebola outbreak in the Eastern Democratic Republic of the Congo: a qualitative study Thu, 25 May 2023 06:00:00 -0400
  CONCLUSIONS: As with other disease outbreaks globally, we found that government mistrust and religious beliefs strongly impacted community perceptions of the EVD outbreak. Previous studies have demonstrated clinic-based medical personnel are often the targets of violence. Our research shows that burial workers were also targeted and exposed to extreme levels of violence in their work. Along with their ability to effectively respond to the outbreak, violence has a negative impact on their own...
• Ebola virus: a new concern, its virological characteristics, diagnosis, present condition, and treatment during the ongoing SARS-CoV-2 omicron variant - correspondence Thu, 25 May 2023 06:00:00 -0400
  No abstract